Sulfasalazine (Azulfidine) dosages for ulcerative colitis vary significantly depending on the severity of the disease and individual patient response. Typical starting doses range from 1-3 grams per day, often divided into multiple administrations.
For mild to moderate ulcerative colitis, doctors frequently prescribe 1-2 grams daily. This dosage is often increased gradually based on clinical improvement. Regular monitoring of blood counts is crucial to detect potential side effects.
Patients with severe ulcerative colitis may require higher doses, up to 4 grams per day, or even higher in some cases. However, higher doses increase the risk of side effects, making careful monitoring even more important.
Maintenance therapy, following successful treatment of an acute flare-up, usually involves a lower dosage, often between 500mg and 1.5 grams per day. The specific maintenance dose depends on individual needs and the physician’s assessment.
Common side effects include nausea, vomiting, diarrhea, and headache. Less frequent, but serious, side effects include allergic reactions and blood disorders. Any unusual symptoms should be reported immediately to a doctor.
Adjustments to the dosage are common. Doctors regularly evaluate patients to assess their response to treatment and adjust the dosage accordingly. This ensures optimal therapeutic benefit while minimizing side effects.
Remember, this information is for general knowledge only. Dosage and treatment should always be determined by a qualified healthcare professional who can consider individual patient factors and tailor the treatment plan accordingly. Always discuss your treatment with your doctor before making any changes to your medication.


