Prednisone works synergistically with Zytiga (abiraterone acetate) to enhance its anti-cancer effects in prostate cancer treatment. This combination therapy improves outcomes compared to Zytiga alone.
Mechanisms of Action
Prednisone, a corticosteroid, reduces the production of certain hormones that fuel prostate cancer growth. Specifically, it suppresses cortisol and other adrenal hormones, increasing the effectiveness of Zytiga’s action. This combined effect leads to a stronger suppression of testosterone levels.
Practical Implications for Patients
- Expect to take prednisone daily, typically at a low dose, alongside your Zytiga. Your doctor will monitor your prednisone dosage based on your individual response and tolerance. Common side effects of prednisone include weight gain, increased appetite, mood changes, and increased blood sugar. Your doctor can help manage these. Regular blood tests will assess your hormone levels and overall response to treatment.
Important Considerations
Prednisone isn’t used alone; it’s always prescribed with Zytiga for metastatic castration-resistant prostate cancer. Your doctor will weigh the benefits of this combination therapy against potential side effects, customized to your health situation. Open communication with your healthcare provider is key to addressing any concerns and managing side effects effectively.
Monitoring and Adjustments
Your treatment plan will be adjusted based on regular monitoring of your PSA levels and overall health. Your doctor will make any necessary changes to your Zytiga and prednisone dosages accordingly. This is a collaborative process focused on optimizing your results and managing potential side effects.
Specific Dosage Information
Dosage of both Zytiga and prednisone vary depending on individual needs and response. Always follow your physician’s instructions carefully.
