Lasix, a powerful diuretic, can sometimes cause blood in the urine (hematuria). This isn’t always a serious problem, but it requires attention. Several factors contribute to Lasix-induced hematuria. Pre-existing kidney conditions, such as kidney stones or glomerulonephritis, can be aggravated by Lasix’s diuretic effect, increasing the likelihood of bleeding. The drug itself can irritate the urinary tract, leading to microscopic hematuria, often unnoticed without a urine test.
Underlying Kidney Issues
Underlying kidney disease significantly increases the risk. Conditions like IgA nephropathy, where inflammation damages the kidneys’ filtering units, are especially sensitive to Lasix. Similarly, individuals with chronic kidney disease (CKD) may experience increased bleeding due to impaired kidney function. Always disclose all pre-existing conditions to your doctor before starting Lasix.
Medication Interactions
Certain medications taken alongside Lasix can heighten the risk of hematuria. Nonsteroidal anti-inflammatory drugs (NSAIDs) are common culprits. NSAIDs can impact kidney function and increase the risk of bleeding. Consult your physician about potential interactions and carefully review all medications.
Dehydration
Lasix’s potent diuretic action can lead to dehydration. Dehydration concentrates urine, potentially irritating the urinary tract and causing bleeding. Maintaining adequate fluid intake while on Lasix is crucial to mitigating this risk. Follow your doctor’s instructions concerning hydration carefully.


