Cialis, or tadalafil, primarily treats benign prostatic hyperplasia (BPH) by relaxing the muscles in the prostate and bladder neck. This relaxation eases urinary flow, reducing symptoms like frequent urination, weak stream, and nighttime awakenings.
This muscle relaxation occurs through the inhibition of phosphodiesterase type 5 (PDE5). PDE5 normally breaks down cyclic guanosine monophosphate (cGMP), a molecule that promotes smooth muscle relaxation. By blocking PDE5, Cialis increases cGMP levels, leading to sustained muscle relaxation in the prostate and bladder neck.
The effect is not limited to the urinary tract. Cialis also affects blood vessels, causing vasodilation. This vasodilation contributes to improved blood flow throughout the body, potentially enhancing erectile function – a common benefit for men with BPH, as erectile dysfunction frequently coexists with the condition.
The duration of Cialis’s action is significant. Unlike some other medications, its effects can last up to 36 hours, allowing for more flexibility in treatment schedules. However, the exact duration and intensity of the effects vary based on individual factors like age, health, and metabolism.
| PDE5 Inhibition | Increased cGMP levels |
| Increased cGMP | Smooth muscle relaxation (prostate & bladder neck) |
| Smooth muscle relaxation | Improved urinary flow |
| Vasodilation | Improved blood flow (potentially enhancing erectile function) |
It’s crucial to consult a healthcare professional to determine the appropriate dosage and monitor for potential side effects. Individual responses to Cialis can differ.
