Ondansetron, the active ingredient in Zofran, can cause several side effects when administered intravenously. Knowing these potential reactions helps manage them effectively.
Most Common Side Effects
- Headache: This is frequently reported. Consider recommending over-the-counter pain relief if needed. Drowsiness: Patients should avoid driving or operating heavy machinery after receiving Zofran IV push. Constipation: Encourage increased fluid intake and fiber consumption to mitigate this. A stool softener may be necessary in severe cases.
Less Frequent, but Important Side Effects
Hypotension: Monitor blood pressure closely, especially in patients with pre-existing cardiovascular conditions. Slow injection rate is crucial. Allergic reactions: While rare, be vigilant for signs like rash, itching, or swelling. Discontinue Zofran immediately and administer appropriate treatment if an allergic reaction occurs. Prolonged QT interval: This is more likely in patients with pre-existing heart conditions or those on other medications affecting the QT interval. ECG monitoring may be warranted in high-risk individuals.
Always review the patient’s medical history and current medications before administering Zofran IV push to minimize the risk of adverse events. If you observe any concerning side effects, consult with a physician immediately.
