Avoid taking amoxicillin/clavulanate with certain medications. Specifically, avoid concurrent use with anticoagulants like warfarin, as amoxicillin can increase bleeding risk. This interaction requires close monitoring by your physician.
Methotrexate is another drug to avoid combining with amoxicillin/clavulanate, as amoxicillin can increase methotrexate’s toxicity. Your doctor will carefully assess your need for both medications.
Allopurinol, used to treat gout, may increase the risk of skin reactions when taken with amoxicillin/clavulanate. Be aware of potential rashes or hives and report them immediately to your doctor.
Oral contraceptives may have reduced effectiveness when combined with amoxicillin/clavulanate. Discuss alternative birth control methods with your doctor during treatment.
| Warfarin | Increased bleeding risk | Close monitoring by physician |
| Methotrexate | Increased methotrexate toxicity | Careful assessment of medication needs |
| Allopurinol | Increased risk of skin reactions | Report rashes or hives immediately |
| Oral Contraceptives | Reduced effectiveness | Discuss alternative birth control |
Inform your doctor of all medications, supplements, and herbal remedies you are taking before starting amoxicillin/clavulanate. This includes over-the-counter drugs. This information is crucial for safe and effective treatment.
