Regularly monitor blood pressure and heart rate. Significant hypotension requires dose adjustment or discontinuation.
Closely track 6-minute walk distance (6MWD) and symptoms like dyspnea and fatigue. Improvements indicate treatment efficacy, while deterioration warrants reevaluation.
Obtain periodic echocardiograms to assess right ventricular function and pulmonary artery pressure. Changes in these parameters guide treatment modifications.
Monitor liver function tests (LFTs) at baseline and periodically thereafter. Elevated LFTs may necessitate dose reduction or treatment cessation.
Be aware of potential visual disturbances, such as blurred vision or altered color perception. These adverse effects are usually mild and transient, but warrant observation.
Assess for headaches, flushing, and nasal congestion. These common side effects usually improve with continued therapy, but may require supportive care.
Encourage patients to report any new or worsening symptoms immediately. Prompt assessment and appropriate management are vital for optimal outcomes.
Discuss potential drug interactions with other medications. Concomitant use of certain drugs may affect sildenafil metabolism and efficacy.
Regularly reassess the patient’s response to therapy and adjust the dosage as needed based on clinical parameters and tolerance. Individualized treatment plans are recommended.
Note: This information is for educational purposes only and does not replace professional medical advice. Always consult with a healthcare provider for personalized guidance regarding sildenafil therapy for PAH.
