Diltiazem can interact with several medications. Grapefruit juice significantly increases diltiazem levels; avoid it. Beta-blockers, when combined, may excessively lower heart rate. Monitor your blood pressure and pulse closely. Digoxin levels can rise with diltiazem use; regular blood tests are needed to maintain safe levels.
Simultaneous use with certain calcium channel blockers (like verapamil) increases the risk of dangerously low blood pressure and heart rate. Your doctor should carefully assess this risk before prescribing both. Rifampin and other medications that induce liver enzymes can reduce diltiazem’s effectiveness. This may necessitate a dose adjustment.
Caution is advised when using diltiazem with statins, as it may increase the risk of myopathy (muscle damage). Regular monitoring of liver function is recommended, especially if you experience muscle pain or weakness.
Inform your doctor about all medications, supplements, and herbal remedies you’re taking before starting diltiazem. This includes over-the-counter drugs. This precaution ensures medication safety and prevents harmful interactions. Regular check-ups with your doctor allow for early detection and management of any side effects.
