Store amoxicillin at room temperature, ideally between 68°F and 77°F (20°C and 25°C). Exceeding these temperatures significantly reduces its potency.
Heat’s Harmful Effects
Exposure to higher temperatures accelerates amoxicillin’s degradation. Prolonged exposure above 86°F (30°C) causes a noticeable decrease in its antibiotic activity. At 104°F (40°C), the degradation rate increases exponentially.
Freezing: A Risky Choice
While freezing might seem like a way to preserve medications, it’s not recommended for amoxicillin. Freezing can alter the drug’s chemical structure, potentially compromising its efficacy and safety.
Optimal Storage Practices
Keep amoxicillin in its original container, tightly closed, away from direct sunlight and moisture. Check the expiration date carefully. Discard any unused medication after that date or if you notice any discoloration or changes in its appearance. Always follow your doctor’s or pharmacist’s instructions regarding dosage and storage.
Consequences of Improper Storage
Using degraded amoxicillin may lead to treatment failure. A weakened antibiotic may not kill the bacteria effectively, resulting in a prolonged or recurring infection. Proper storage prevents these risks, ensuring the medication works as intended.


