Calcitriol, while beneficial for treating vitamin D deficiency and related conditions, can cause side effects. Common side effects include headache, nausea, vomiting, and constipation. Less common, but potentially serious, side effects include kidney stones and irregular heartbeat. Always report any unusual symptoms to your doctor.
Potential Drug Interactions
Calcitriol interacts with several medications. This interaction can either increase the effectiveness of other drugs or reduce it, potentially leading to adverse effects. For example, thiazide diuretics, commonly used to treat high blood pressure, can increase calcium levels in the blood, potentially exacerbating the effects of calcitriol. Conversely, some anticonvulsants may reduce calcitriol absorption. This list isn’t exhaustive; it’s vital to inform your doctor about all medications, supplements, and herbal remedies you are taking before starting calcitriol.
Monitoring Calcium Levels
Regular monitoring of your calcium levels is crucial while on calcitriol. High blood calcium levels (hypercalcemia) are a serious side effect and can lead to complications. Your doctor will likely order blood tests to check your calcium levels at regular intervals to ensure safe and effective treatment.
| Thiazide Diuretics | Increased calcium absorption | Risk of hypercalcemia |
| Digoxin | Increased risk of cardiac arrhythmias | Monitor heart rhythm closely |
| Phenytoin (Dilantin) | Decreased calcitriol absorption | May require dose adjustment |
Remember, this information is for educational purposes only and does not replace professional medical advice. Always consult your doctor or pharmacist before starting or stopping any medication, including calcitriol.


