Clindamycin combats acne by targeting Propionibacterium acnes (P. acnes), a bacterium frequently implicated in acne development. This antibiotic disrupts bacterial protein synthesis, preventing P. acnes from multiplying and causing inflammation.
Doctors often prescribe clindamycin in combination with other acne treatments, such as benzoyl peroxide. Benzoyl peroxide kills P. acnes directly, while clindamycin prevents it from growing back. This synergistic approach boosts treatment success.
Oral clindamycin is generally reserved for moderate to severe acne that hasn’t responded adequately to topical treatments. Your dermatologist will consider your individual skin condition, medical history, and potential side effects before recommending this course.
Common side effects include diarrhea, stomach upset, and vaginal yeast infections. Serious side effects are rare, but include Clostridium difficile-associated diarrhea, a potentially dangerous bowel infection. Report any significant side effects immediately to your physician.
Remember: Clindamycin is a prescription medication. Always follow your doctor’s instructions precisely regarding dosage and duration of treatment. Avoid self-treating acne; a proper diagnosis and treatment plan from a dermatologist are paramount.
Consistent use is key to achieving the best results. Clindamycin may take several weeks to show noticeable improvement. Be patient and continue the treatment as directed. Regular check-ups with your dermatologist will allow for monitoring progress and adjusting treatment if needed.


