Begin doxycycline within 72 hours of a tick bite. This timeframe maximizes its effectiveness in preventing Lyme disease. Continue taking the medication for the full prescribed course, usually 2-4 weeks, even if symptoms haven’t appeared. Stopping early reduces its protective effect.
Factors Influencing Duration
Your doctor determines the exact duration based on several factors. These include the type of tick involved, the area where the bite occurred (risk of Lyme disease varies geographically), and your overall health. They’ll carefully assess your individual risk and prescribe accordingly. Always follow their instructions precisely.
If you develop symptoms suggestive of Lyme disease such as fever, headache, rash, or joint pain during or after prophylaxis, contact your doctor immediately. They may recommend further testing and adjust your treatment plan.


