Discontinuation of Labetalol Infusion

Gradually reduce the Labetalol infusion rate by 25-50% every 15-30 minutes, depending on the patient’s response and hemodynamic stability. Monitor blood pressure and heart rate continuously during this process. Target a gradual decline in blood pressure, aiming for a reduction not exceeding 25% of the initial baseline in any given 30-minute period.

Closely observe for signs of rebound hypertension or tachycardia. If these occur, temporarily halt the reduction or adjust the rate more slowly. Consider administering oral Labetalol or other antihypertensive medication to maintain hemodynamic stability once the infusion is stopped.

Complete cessation of the infusion should be confirmed by the discontinuation of the intravenous line. Post-infusion monitoring should continue for at least one hour, including continuous blood pressure and heart rate monitoring. Assess the patient’s overall condition, including any adverse effects.

Discharge instructions should include clear guidelines on oral antihypertensive medication continuation and advice for follow-up appointments. Provide clear information about potential side effects and what actions to take should they occur.

Document all changes in infusion rate, blood pressure, heart rate, and any observed side effects throughout the process and afterwards. Maintain accurate records in the patient’s medical chart.