Simultaneous use of ranitidine and prednisone can increase the risk of osteoporosis. Prednisone weakens bones, and ranitidine, while not directly impacting bone density, might indirectly affect calcium absorption which is crucial for bone health. Discuss bone density monitoring with your doctor, especially if you’re already at risk for osteoporosis.
Gastrointestinal Effects
Ranitidine reduces stomach acid. Prednisone, however, can irritate the stomach lining. This combination might mask symptoms of a peptic ulcer or stomach irritation caused by prednisone, delaying diagnosis and treatment. Report any persistent stomach pain or discomfort to your healthcare provider immediately.
Other Potential Interactions
While less common, monitor for increased susceptibility to infections. Both medications can potentially suppress your immune system. Pay attention to any new or worsening signs of infection, such as fever, chills, or persistent cough. Report these symptoms promptly to your doctor.
