Methotrexate often serves as a first-line immunosuppressant for conditions like rheumatoid arthritis and psoriasis. It effectively reduces inflammation and slows disease progression. Close monitoring of liver function and blood counts is necessary.
Alternative Immunosuppressants
Azathioprine provides another option, particularly useful for inflammatory bowel disease and lupus. Like methotrexate, regular blood tests track potential side effects. Mycophenolate mofetil offers targeted immunosuppression, often used for transplant recipients but also finding application in certain autoimmune disorders. It requires careful monitoring for gastrointestinal side effects. Cyclosporine, while effective for some autoimmune conditions, carries a higher risk of kidney damage and hypertension, demanding close medical supervision.
Biologics, such as TNF inhibitors (e. g., infliximab, adalimumab) and interleukin-1 blockers, represent a newer class of drugs. They target specific components of the immune system, offering tailored treatment. While often highly effective, infusion reactions or increased susceptibility to infections are potential complications. Each medication presents a unique profile; a physician’s guidance is vital in selecting the best treatment plan tailored to your specific condition and health status.
