Always inform your doctor or pharmacist about all medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. This includes prescription medications, such as:
- Ketoconazole or Itraconazole: These antifungal medications can increase budesonide levels in your body, potentially leading to increased side effects. Your doctor may adjust your budesonide dose. Ritonavir or other HIV protease inhibitors: Similar to antifungals, these medications can also raise budesonide blood levels. Careful monitoring and potential dose adjustments are necessary. CYP3A4 inducers (e. g., rifampin, St. John’s Wort): These medications can reduce budesonide levels, potentially decreasing its effectiveness. Your doctor might need to increase your budesonide dose or consider an alternative treatment.
Grapefruit juice can also interact with budesonide metabolism. Avoid consuming large quantities of grapefruit juice while taking this medication.
For a complete and updated list of potential interactions, consult your doctor or pharmacist or check the medication’s package insert. They can assess your individual circumstances and provide personalized advice.
Report any new or worsening symptoms to your healthcare provider immediately. This proactive approach ensures your safety and treatment effectiveness.


