Closely monitor patients for common side effects. Regular blood tests are crucial for tracking liver function and electrolyte levels.
Address hyperglycemia proactively. Consider dietary adjustments and possibly metformin if blood glucose remains elevated.
- Encourage a balanced diet low in simple sugars. Regular blood glucose monitoring is recommended.
Manage fluid retention. Monitor weight daily, restrict sodium intake, and consider diuretics if edema develops. A low-sodium diet is particularly important.
- Weigh patients daily at the same time. Provide clear dietary guidance on sodium restriction.
Prevent and treat osteoporosis. Encourage weight-bearing exercise and consider supplementation with calcium and Vitamin D. Regular bone density scans may be warranted.
- Discuss appropriate exercise regimens with patients. Refer for bone density assessment as clinically indicated.
Reduce gastrointestinal distress. Administer prednisolone with food to minimize stomach upset. Antacids or proton pump inhibitors might be necessary if symptoms persist.
Monitor for signs of infection. Prednisolone suppresses the immune system, increasing infection susceptibility. Prompt treatment of any infection is vital.
Address psychological side effects. Prednisolone can cause mood swings, anxiety, and insomnia. Counseling or medication adjustments might be necessary.
Patient education about potential psychological effects is key. Consider referring patients to mental health professionals if needed.
Taper prednisolone gradually. Abrupt cessation can cause adrenal insufficiency. A slow reduction under medical supervision is essential to minimize withdrawal symptoms.
Regularly reassess the need for prednisolone. Continuously evaluate the benefit-risk ratio. Consider alternative treatments if possible.


