Sildenafil requires careful consideration for certain patient groups. Always consult your doctor before starting treatment.
Patients with Cardiovascular Disease
- Individuals with unstable angina, recent myocardial infarction, or uncontrolled heart failure should avoid sildenafil. The drug can place additional strain on the heart. Patients with known coronary artery disease should undergo a thorough cardiovascular evaluation before starting therapy. This may involve an electrocardiogram and discussion of risk factors. Monitor blood pressure closely, especially after initiating sildenafil, as hypotension can occur.
Patients with Liver or Kidney Disease
Sildenafil is primarily metabolized by the liver and excreted by the kidneys. Dosage adjustments may be necessary for patients with impaired liver or kidney function to prevent accumulation of the drug and potential adverse effects.
Lower starting doses are typically recommended. Your doctor will determine the appropriate dose based on your individual needs and medical history. Close monitoring of renal and hepatic function is recommended during treatment.
Patients with Retinitis Pigmentosa
Individuals with a history of retinitis pigmentosa should exercise caution when considering sildenafil. Rare cases of visual disturbances have been reported. Discuss this thoroughly with your physician.
Patients Taking Other Medications
- Sildenafil can interact with several medications, including nitrates, alpha-blockers, and certain antifungal agents. These interactions can cause a significant drop in blood pressure. Always provide your physician with a complete list of all medications, supplements, and herbal remedies you are taking.
Older Adults
Older adults may be more sensitive to the effects of sildenafil, and dosage adjustments may be needed. Close monitoring is recommended. Your physician will determine the appropriate course of treatment.
