Apply a thin layer of Mupirocin or Polysporin ointment directly to the affected area three times daily. For Mupirocin, use a pea-sized amount; for Polysporin, follow the instructions on the packaging. Gently rub the ointment in until it’s absorbed.
Continue treatment for at least 7 days, or until the infection clears. If no improvement is seen within 3-5 days, consult a doctor. Do not use these ointments for more than 10 days at a time, even if the infection persists. Always wash your hands thoroughly before and after application. Avoid contact with eyes and other mucous membranes.
Mupirocin Specific Precautions
Mupirocin is primarily for bacterial skin infections. Avoid use on large areas of skin or open wounds. Inform your doctor if you’re allergic to any antibiotics. Pregnancy and breastfeeding require specific medical advice regarding Mupirocin use.
Polysporin Specific Precautions
Polysporin often contains bacitracin and neomycin. Allergic reactions, particularly to neomycin, are possible. Observe for signs of allergic reactions such as swelling, rash, or itching. Stop use and contact a healthcare professional if you experience any allergic reactions.
| Mupirocin | Pea-sized amount, 3 times daily | 7-10 days | Avoid large areas, open wounds; inform doctor of allergies. |
| Polysporin | Follow package instructions | 7-10 days | Watch for allergic reactions; stop use if allergy occurs. |
This information is for guidance only; always follow your doctor’s instructions and read the product label carefully before using either ointment. Never self-diagnose or self-treat serious infections.


