Tadalafil 5mg works by inhibiting the phosphodiesterase-5 (PDE5) enzyme. This enzyme breaks down cyclic guanosine monophosphate (cGMP), a molecule crucial for blood vessel relaxation.
Increased Blood Flow
By blocking PDE5, Tadalafil increases cGMP levels. Higher cGMP levels cause the smooth muscles in blood vessels to relax, leading to increased blood flow, particularly in the penis.
Improved Erections
This enhanced blood flow facilitates penile engorgement and contributes to improved erectile function. The effect is targeted; Tadalafil doesn’t directly stimulate the penis but rather optimizes its response to sexual stimulation.
Duration of Action
Tadalafil’s relatively long half-life allows for a sustained effect, often lasting up to 36 hours. This extended duration differentiates it from other similar medications.