Sildenafil citrate is the active pharmaceutical ingredient in both Revatio and Viagra. It works by inhibiting phosphodiesterase-5 (PDE5), an enzyme that breaks down cyclic guanosine monophosphate (cGMP).
How Sildenafil Citrate Works
Increased cGMP levels relax the smooth muscles in the blood vessels of the penis, allowing for increased blood flow. This mechanism is crucial for achieving and maintaining an erection.
- Viagra uses higher doses of sildenafil citrate to specifically treat erectile dysfunction. Revatio employs lower doses to treat pulmonary arterial hypertension (PAH), a condition affecting blood vessels in the lungs.
The difference in dosage reflects the distinct physiological targets and desired effects.
Important Considerations Regarding Sildenafil Citrate
Always follow your doctor’s prescribed dosage. Discuss potential drug interactions with your physician before taking sildenafil citrate, especially regarding nitrates. Report any adverse effects, such as headaches, flushing, or visual disturbances, to your doctor immediately. Sildenafil citrate isn’t suitable for everyone; factors such as heart conditions and previous strokes must be considered.
Dosage Differences: Revatio vs. Viagra
The concentration of sildenafil citrate varies significantly. Revatio is available in 20 mg tablets, while Viagra comes in various strengths, typically ranging from 25 mg to 100 mg. This difference in concentration directly relates to the intended use and the severity of the condition being treated. Always consult with a healthcare professional for proper guidance.
